Travis Bruno of Capsule Computers writes:
"Many stories revolve around a puzzle of some kind, whether it be a murder mystery, discovering clues to track down a thief or some other crime related drama to survival situations. However despite the prevalence of puzzles in most stories, few take the risk of focusing entirely around solving puzzles as a plot point. Enter Phi-Brain: Puzzle of God, a series which revolves around just that, solving various puzzles. Now that Sentai Filmworks has brought the series overseas in Season One: Collection One, does this formula create something worthwhile?"