Travis Bruno of Capsule Computers writes:
"A virus originating from the Bugs 2 expedition to Mars with a one hundred percent mortality rate has started to sweep throughout the planet Earth. In an effort to find a cure for this virus and save the world, numerous nations have teamed together to send a large force to Mars called Annex 1 where they will try to capture mutated cockroaches and find a cure. However that is far easier said than done as not only have these cockroaches become smarter since Bugs 2, new and extremely powerful variants have already caused the deaths of many crewmembers. With the crew in trouble and facing off against foes they are ill-prepared to handle, what will happen in Terra Formars Volume 4?"