Travis Bruno of Capsule Computers writes:
"The concept of using amnesia as a storytelling device is incredibly common in most forms of media. In video games it tends to be a method to place players in a role of a grown protagonist who is a blank slate and can be built from there. However while amnesia in stories is usually used for to set up a story, rarely does an entire story focus around someone suffering from constant memory loss. <em>One Week Friends</em> is such a series and after a successful manga run the source material has been adapted into an anime. The question is, is this series worth remembering?"